Nucleic acid amplification tests are the gold standard for many infectious disease diagnoses due to high sensitivity and specificity, rapid operation, and low limits of detection. Despite the advantages of nucleic acid amplification tests, they currently offer limited point-of-care (POC) utility due to the need for complex instruments and laborious sample preparation. We report the development… Read more »
There is a need for new methodologies to quickly assess the presence and reactivity of nanoparticles (NPs) in commercial, environmental, and biological samples since current detection techniques require expensive and complex analytical instrumentation. Here, we investigate a simple and portable colorimetric detection assay that assesses the surface reactivity of NPs, which can be used to… Read more »
Lateral flow immunoassays (LFA) are one of the most prevalent point-of-care (POC) diagnostics due to their simplicity, low cost, and robust operation. A common criticism of LFA tests is that they have poor detection limits compared to analytical techniques, like ELISA, which confines their application as a diagnostic tool. The low detection limit of LFA… Read more »
UW Chemical Engineering has recognized Charlie Corredor with the Faculty Lecture Award. The Faculty Lecture Award is based on the overall scholarly nature and productivity of the student. Charlie gave an award lecture to students and faculty on this work on Environmental and Toxicological Nanotechnology. Charlie has published 11 papers and has an h-index of… Read more »
Congratulations to Babak Y. Moghadam for defending this thesis and completing all requirements for his PhD.
Paper substrates have been widely used to construct point-of-care lateral flow immunoassays (LFIA) diagnostic devices. Paper based microfluidic devices are robust and relatively simple to operate, compared to channel microfluidic devices, which is perhaps their greatest advantage and the reason they have reached a high level of commercial success. However, paper devices may not be… Read more »
Catalytic bimetallic Janus particles swim by a bipolar electrochemical propulsion mechanism that results from electroosmotic fluid slip around the particle surface. The flow is driven by electrical body forces which are generated from a coupling of a reaction-induced electric field and net charge in the diffuse layer surrounding the particle. This paper presents simulations, scaling,… Read more »
Styrene-ethylene/butylene-styrene (SEBS) copolymers combine thermoplastic and elastomeric properties to provide microdevices with the advantageous properties of hard thermoplastics and ease of fabrication similar to PDMS. This work describes the electrical surface properties of SEBS block copolymers using current monitoring experiments to determine zeta potential. We show that SEBS exhibits a stable and relatively high zeta… Read more »