The University of Washington in Seattle, Washington seeks to fill a full-time acting assistant professor or post-doctoral research associate position. The proposed position focuses on the development of a point-of-care diagnostic for detecting small molecules for the adherence to HIV antiretroviral therapy. The successful candidate will work in Jonathan Posner’s research group, will have an appointment in either the Departments of Mechanical Engineering or Chemical Engineering, and will work closely with our project collaborators at PATH (Seattle, WA) and UW Division Allergy of Infectious Diseases.
This NIH funded project focuses on the development of a rapid, point-of-care diagnostic adherence to HIV antiretroviral therapy (ART) drugs. Oral antiretroviral therapy (ART) is highly effective for HIV-infected people to prevent transmission and HIV-uninfected people to prevent acquisition, known as pre-exposure prophylaxis (PrEP), but monitoring and improving drug adherence have been challenging. However, ART and PrEP are only effective when people maintain adequate adherence (≥4 doses per week). As many patients taking ART or PrEP have difficulty with adherence, clinicians currently have no available tools to monitor drug levels or adherence to provide targeted counseling and support. We are seeking researchers to develop a rapid point-of-care (POC) assay to monitor ART or PrEP drug adherence.
The project is experimentally intensive and involves the construction of point-of-care immunoassays. Successful candidates will have a passion for technical solutions to challenges in global health and demonstrated experience in any of the following areas: point of care diagnostics, immunoassays, paper microfluidics, biochemistry and/or electrolyte chemistry, ELISA, and/or surface plasmon resonance. A PhD in engineering, chemistry, physics, biology, or related field is required. Candidates should have published in peer-reviewed publications, work well in a team, and have strong communication skills.
To apply, please send electronically a cover letter, a CV, and the names and contact information for three references to Jonathan Posner at jposner@uw.edu.
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