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ES&T Cover!

The catalytic properties of nanoparticles have been leveraged to develop a sensitive and simple colorimetric methodology for detection of metal and oxide nanoparticles in complex media.  Image of assay’s reaction was selected as the cover image of the journal ES&T.   This work was highlighted by NSF via twitter  

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ES&T publication by Charlie and Prof.Posner was highlighted on Nanowerk

A team led by Jonathan D. Posner, Bryan T. McMinn Endowed Associate Professor at UW, developed a colorimetric assay – similar to a swimming pool test kit – that tests for the presence or absence of nanoparticles in biological and environmental relevant samples with sufficient sensitivity as part per billion concentration levels. Full article here

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Mark and Kevin published their work on Nucleic Acid detection using Isotachophoresis and Loop-mediated isothermal amplification in Lab on a Chip

Nucleic acid amplification tests are the
 gold standard for many infectious disease
diagnoses due to high sensitivity and specificity, rapid operation, and low limits of detection. Despite the advantages of nucleic acid amplification tests, they currently offer limited point-of-care 
(POC) utility due to the need for complex instruments and laborious sample preparation. We report the development… Read more »

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Charlie, Jay and Mark published their work on colorimetric detection of catalytic reactivity of nanoparticles in complex matrices in ES&T

There is a need for new methodologies to quickly assess the presence and reactivity of nanoparticles (NPs) in commercial, environmental, and biological samples since current detection techniques require expensive and complex analytical instrumentation. Here, we investigate a simple and portable colorimetric detection assay that assesses the surface reactivity of NPs, which can be used to… Read more »

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Babak and Kelly published their work on improvement in detection limit of lateral flow assays using isotachophoresis in Analytical Chem

Lateral flow immunoassays (LFA) are one of the most prevalent point-of-care (POC) diagnostics due to their simplicity, low cost, and robust operation. A common criticism of LFA tests is that they have poor detection limits compared to analytical techniques, like ELISA, which confines their application as a diagnostic tool. The low detection limit of LFA… Read more »